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ACTA MÉDICA PORTUGUESA 2003; 16: 225-228
ATIPIAS GLANDULARES DE SIGNIFICADO
INDETERMINADO (AGUS)
QUE ENTIDADE ?
M.ª ADELAIDE PIRES, M.ª TERESA REBELO, MARGARIDA F. DIAS, NATÁLIA AMARAL, MADALENA DINIS,
CARLOS F. OLIVEIRA, HENRIQUE M. OLIVEIRA
Serviços de Ginecologia e Anatomia Patologica. Hospitais da Universidade de Coimbra. Coimbra
RESUMO/SUMMARY
ATYPICAL GLANDULAR CELLS OF
UNDETERMINED SIGNIFICANCE (AGUS)
WHICH ENTITY?
OBJECTIVE : The aim of this study was to determine the incidence and evolution of the atypical glandular cells of undetermined significance (AGUS) without associated lesions identified on cervical Pap smear. MATERIAL
AND METHODS : Retrospective study concerning
33.923 cervicovaginal smears performed in the
Cytopathology Department of the Coimbra
University Hospital (H.U.C.) between January
1995 an December 1997. AGUS diagnosis, isolated or associated with other lesions, was made in 716 cases. Four hundred fourty-four of them were refered to patiens of the H.U.C. Ginecology
Department. One hundred seventy-seven cases were classified as AGUS alone; 62 related to the
Ginecology Department where follow-up was performed within a period from 3 to 36 months.
This study concerns exclusively AGUS patients without associated lesions (N=62). RESULTS:
Sixty two cases of isolated AGUS were studied; the incidence was 0,52% and the average age 44,7
±11,7 [19-75] years old. Follow-up, performed between 3 and 36 months, revealed: isolated cervical smears (N=9), cervical smears and endocervical curettage (N=15), cervical smears with colposcopy and directed biopsy and/or endocervical curettage (N=11), cervical smears and
colposcopy