Referencias de trabalho

http://www.ncbi.nlm.nih.gov/pubmed/23006668
1. Katchanov J, Birbeck GL. Epilepsy in the WHO Africa region, Bridging the Gap: The Global campaign against epilepsy “Out of the Shadows”. Geneva: WHO; 2004.
2. Ngugi AK, Bottomley C, Kleinschmidt I, Sander JW, Newton CR. Estimation of the burden of active and life-time epilepsy: a meta-analytic approach. Epilepsia. 2010;51:883–890.
3. Moreira SRG. Epilepsia: concepção histórica, aspectos conceituais, diagnóstico e tratamento. Mental . II - n. 3 - Barbacena - nov. 2004 - p. 107-122.
4. PLoS One. 2013;8(1):e54515. doi: 10.1371/journal.pone.0054515. Epub 2013 Jan 21.
Seizures induced by pentylenetetrazole in the adult zebrafish: a detailed behavioral characterization.
Mussulini BH, Leite CE, Zenki KC, Moro L, Baggio S, Rico EP, Rosemberg DB, Dias RD, Souza TM, Calcagnotto ME, Campos MM, Battastini AM, de Oliveira DL.

1. http://jpet.aspetjournals.org/content/298/3/986.full http://www.ncbi.nlm.nih.gov/pubmed/11504794 2. http://www.comciencia.br/reportagens/epilepsia/ep24.htm
3. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-26492006000200003
4. http://www.scielo.br/scielo.php?pid=S0004-282X2009000400019&script=sci_arttext
5. http://www.ncbi.nlm.nih.gov/pubmed/15909663
6. http://www.ncbi.nlm.nih.gov/pubmed/12000037

Gilbert, M. E. Does the kindling model of epilepsy contribute to our understanding of multiple chemical sensitivity?. Annals of the New York Academy of Sciences. 2001 Mar;933:68-91.

Godukhin, O. V. [Cellular-molecular mechanisms of kindling]. Uspekhi Fiziologicheskikh Nauk. 2005 Apr-Jun;36(2):41-54.
Queiroz
João Leite
Luiz Eugênio Mello

Os modelos animais são voltados para entender quais são os mecanismos neurais responsáveis pelas epilepsias humanas e a produção de novos fármacos e/ou abordagens terapêuticas, logo, inibe antagonizando competitivamente o receptor GABAA, provavelmente através de uma interação alostérica no canal Cl- resultando na