Estudo prospectivo da utilização do aloe vera nas afecções da cavidade anoftálmica em portadores de prótese ocular

burns 33 (2007) 713–718

available at www.sciencedirect.com

journal homepage: www.elsevier.com/locate/burns

The efficacy of aloe vera used for burn wound healing:
A systematic review
Ratree Maenthaisong a,b, Nathorn Chaiyakunapruk a,*, Surachet Niruntraporn c,
Chuenjid Kongkaew a a Pharmacy Practice Unit, Department of Pharmacy Practice, Naresuan University, Phitsanulok, Thailand
Department of Clinical Pharmacy and Research, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand c Department of Pharmacy Practice, Naresuan University (Phayao Campus), Phayao, Thailand b article info

abstract

Article history:

Aloe vera has been traditionally used for burn healing but clinical evidence remains unclear.

Accepted 10 October 2006

We conducted a systematic review to determine the efficacy of topical aloe vera for the treatment of burn wounds. We electronically searched relevant studies in MEDLINE,

Keywords:

CINAHL, Cochrane Library, HealthSTAR, DARE, South-East Asia Database, Chinese Data-

Aloe vera

bases, and several Thai local Databases (1918–June 2004). Only controlled clinical trials for

Burn

burn healing were included. There were no restrictions on any language of publication. Two

Systematic review

reviewers independently extracted data on study characteristics, patient characteristics, intervention, and outcome measure.
Four studies with a total of 371 patients were included in this review. Based on a metaanalysis using duration of wound healing as an outcome measure, the summary weighted mean difference in healing time of the aloe vera group was 8.79 days shorter than those in the control group (P = 0.006). Due to the differences of products and outcome measures, there is paucity to draw a specific conclusion regarding the effect of aloe vera for burn wound healing. However, cumulative evidence tends to support that aloe vera might be an effective interventions used in burn wound healing