Bacterial larvicidas

WHO/CDS/CPC/WHOPES/99.2 ENGLISH ONLY DISTR.: LIMITED

DRAFT Guideline specifications for bacterial larvicides for public health use
Report of the WHO Informal Consultation 28-30 April 1999 WHO, Geneva

World Health Organization Communicable Diseases Prevention and Control WHO Pesticide Evaluation Scheme (WHOPES)

This document is not issued to the general public, and all rights are reserved by the World Health Organization (WHO). The document may not be reviewed, abstracted, quoted, reproduced or translated, in part or in whole, without the prior written permission of WHO. No part of this document may be stored in a retrieval system or transmitted in any form or by any means – electronic, mechanical or other – without the prior written permission of WHO.

Contents
Page

1. 2.

Introduction Role of Bacterial Larvicides in Public Health 2.1 2.2 2.3 2.4 Current Uses Integrated Control Potential for Resistance Future Prospects for Bacterial Larvicides

1 1 2 3 3 4 4

3.

Registration Requirements, Including Quality Control and Safety Requirements for Bacterial Larvicides Guideline Specifications for Bacterial Larvicides 4.1. Technical and Formulation-Specific Requirements and Objectives for Their Inclusion in the Specifications 4.1.1 Description of the Product 4.1.2 Active Ingredient 4.1.3 Physical and Physico-chemical Properties 4.1.4 Packaging 4.1.5 Labelling Guideline Specifications for Technical Concentrate and Common Formulations of Bacterial Larvicides 4.2.1 4.2.2 4.2.3 4.2.4 4.2.5 Technical Concentrate (TK) Aqueous Suspension Concentrate (SC) Water Dispersible Granule (WG) Wettable Powder (WP) Water Dispersible Tablet (WT)

4.

9 9

10 11 11 12 13 13

4.2.

13 15 18 21 24 28 29

5. 6.

Recommendations Annex 1. Determination of the toxicity of Bacillus thuringiensis subsp. israelensis and B. sphaericus Products Annex 2. List of Participants

32

WHO/CDS/CPC/WHOPES/99.2 Page1

1.

Introduction

Dr Arata Kochi, the