Artigo Trabalho De Qu Mica

http://dx.doi.org/10.5935/0100-4042.20150035

Quim. Nova, Vol. 38, No. 4, 538-552, 2015

Revisão

CURCUMINA, O PÓ DOURADO DO AÇAFRÃO-DA-TERRA: INTROSPECÇÕES SOBRE QUÍMICA E
ATIVIDADES BIOLÓGICAS
Vitor Sueth-Santiagoa, Gustavo Peron Mendes-Silvaa, Débora Decoté-Ricardob e Marco Edilson Freire de Limaa,* a Departamento de Química, Instituto de Ciências Exatas, Universidade Federal Rural do Rio de Janeiro, BR 465, Km 07, 23897‑000
Seropédica – RJ, Brasil b Departamento de Microbiologia, Imunologia e Virologia Veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, BR 465, Km 07, 23897-000 Seropédica – RJ, Brasil
Recebido em 01/08/2014; aceito em 12/12/2014; publicado na web em 05/03/2015

CURCUMIN, THE GOLDEN POWDER FROM TURMERIC: INSIGHTS INTO CHEMICAL AND BIOLOGICAL ACTIVITIES.
Turmeric, obtained from the dried rhizomes of Curcuma longa (Zingiberaceae), is a golden colored material, commonly used around the world for seasoning and coloring food dishes. Since antiquity, turmeric has been widely used in the treatment of several diseases in traditional Chinese and Indian medicine (Ayurveda), where it is also known by other names such as Kanchani (goddess gold) or also Gauri (having a bright and luminous face), a designation stemming from the gilded appearance of the plant material.
Curcumin, the main chemical component of turmeric, is responsible both for its properties as dyes as well as its biological activities.
This diarylheptanoid was first isolated almost two centuries ago and had its chemical structure determined in 1910 as being diferuloylmethane. Subsequently, more detailed and relevant data were obtained furthering the understanding of structural features of curcumin. The classical methodology for the synthesis of curcumin and other curcuminoids was described in 1960 by Pabon.
Subsequently, different variations on this methodology have been developed, culminating with the synthesis of different curcuminoids.
Several studies have